1/7/2024 0 Comments Metaz cream usesSkin cancer precursor immunotherapy for squamous cell carcinoma prevention. Local treatment other than surgery for basal and squamous cell skin cancers.Topical chemotherapy in cutaneous T-cell lymphoma: Positive results of a randomized, controlled, multicenter trial testing the efficacy and safety of a novel mechlorethamine, 0.02%, gel in mycosis fungoides. Combination topical chemotherapy for the treatment of an invasive cutaneous squamous cell carcinoma. Topical and intralesional treatment of nonmelanoma skin cancer: Efficacy and cost comparisons. Topical chemotherapy for giant ocular surface squamous neoplasia of the conjunctiva and cornea: Is surgery necessary? You can learn more about how we ensure our content is accurate and current by reading our editorial policy. We link primary sources - including studies, scientific references, and statistics - within each article and also list them in the resources section at the bottom of our articles. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. The gel shrunk the participants’ tumors by 58.5%, and the ointment shrunk them by 47.7%. The study compared a gel with a compounded ointment. There is limited research suggesting that certain types of chemotherapy cream may help skin manifestations of other cancers.įor example, a 2013 study tested mechlorethamine cream in people with T cell lymphoma who had mycosis fungoides, which is a skin manifestation of lymphoma. Chemotherapy cream did not reduce the risk of keratinocyte carcinomas, but surgery did. The specific benefits of chemotherapy cream to prevent cancer depend on the type of cancer a doctor wants to prevent.įor example, a 2018 randomized clinical trial found a 75% reduction in the risk of developing squamous cell carcinoma in the first year following treatment with chemotherapy cream.Īlthough there was a slight reduction in the risk of basal cell carcinoma, the reduction was not statistically significant. Type of cancer may determine type of cream For example, doctors may prescribe 5FU cream to people with actinic keratosis, which is a type of sun-related skin damage that can lead to skin cancer. A 2019 study suggested that chemotherapy cream, when a person uses it with other treatments, can reduce the risk of developing skin cancer.Methotrexate cured 91% of cancers, compared with a higher cure rate of 98% for 5FU cream. Keratoacanthoma, which is a type of squamous cell carcinoma, had the highest cure rate with chemotherapy cream.
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